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• Relationship between breast cancer risk factors and mammographic breast densi...

• Triplets versus doublets, with or without cisplatin, in the first-line treatm...

• Exposure to animals and increased risk of marginal zone B-cell lymphomas of t...

• Functional imaging: what evidence is there for its utility in clinical trials...

• Sigma-2 ligands induce tumour cell death by multiple signalling pathways

• The BH3 mimetic HA14-1 enhances 5-fluorouracil-induced autophagy and type II ...

• Uptake of risk-reducing salpingo-oophorectomy in women carrying a BRCA1 or BR...

• CA-125 can be part of the tumour evaluation criteria in ovarian cancer trials...

• Gallstones and cholecystectomy in relation to risk of intra- and extrahepatic...

• Open-label feasibility study of pazopanib, carboplatin, and paclitaxel in wom...

• A novel pathway combining calreticulin exposure and ATP secretion in immunoge...
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell deathUnravelling molecular mechanisms that trigger immunogenic apoptosis of cancer cells could improve therapeutic intervention. Here, photo-oxidative ER stress increases presentation of ?eat me? (surface-exposed calreticulin) and ?find me? (ATP secretion) signals via a novel, PERK-dependent pathway.

• A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerizatio...
A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAXDepending on the context, cells either arrest or undergo apoptosis in response to p53 activation. Key mediators of both pathways are activated irrespective of the fate choice, but apoptotic cells selectively induce the DR4 death receptor pathway, caspase 8-mediated BID cleavage and activation of BAX.

• Enlightening the impact of immunogenic cell death in photodynamic cancer therapy
Enlightening the impact of immunogenic cell death in photodynamic cancer therapyThis feature highlights novel molecular pathways underlying the cell surface presentation of calreticulin and ATP secretion, critical damage-associated molecular patterns (DAMPs) that trigger immunogenic cell death.

• Evolutionary conserved longevity genes and human cognitive abilities in elder...

• Researchers? opinions towards the communication of results of biobank researc...

• Intellectual disability associated with retinal dystrophy in the Xp11.3 delet...

• Prospective comparison of family medical history with personal genome screeni...

• 8q23.3 and 11q23.1 as modifying loci influencing the risk for CRC in Lynch sy...

• Association between survivin ?31G>C promoter polymorphism and cancer risk: a ...

• Genetic correlations and the evolution of photoperiodic time measurement with...

• An evolutionarily and ecologically focused strategy for genome sequencing eff...

• Parallel signatures of sequence evolution among hearing genes in echolocating...

• Hybrid fitness, adaptation and evolutionary diversification: lessons learned ...

• Microevolution of sympatry: landscape genetics of hedgehogs Erinaceus europae...

• Genetics and evolution of triatomines: from phylogeny to vector control

• Genetic drift and rapid evolution of viviparity in insular fire salamanders (...

• From adaptation to molecular evolution

• Evolution of adaptive phenotypic traits without positive Darwinian selection

• Body mass index classification misses subjects with increased cardiometabolic...

• A bi-directional relationship between obesity and health-related quality of l...

• The risk of general and abdominal adiposity in the occurrence of new vascular...

• Low risk HLA-DQ and increased body mass index in newly diagnosed type 1 diabe...

• Induction of fatty acid oxidation resists weight gain, ameliorates hepatic st...

• Metabolic syndrome is associated with increased risk of recurrent colorectal ...

• The identification of two subgroups of obese women with differing endometrial...

• Is funding source related to study reporting quality in obesity or nutrition ...

• Childhood psychological function and obesity risk across the lifecourse: find...

• Maternal and infant factors associated with neonatal adiposity: Results from ...

• Association between dietary scores and 13-year weight change and obesity risk...

• Effect of dairy consumption on weight and body composition in adults: a syste...

• Hip circumference is associated with the risk of premenopausal ER?/PR? breast...

• Dietary fat intake and polymorphisms at the PPARG locus modulate BMI and type...

• Association of baseline sex hormone levels with baseline and longitudinal cha...

• Feasibility of using web surveys to collect time?activity data

• Exposure to organochlorine pesticides is an independent risk factor of hepato...

• The diagnostic performance of mid-regional portion of pro-atrial natriuretic ...

• Perception of uncontrolled blood pressure and behaviours to improve blood pre...

• Cardiovascular risk factor(s) prevalence in Greek hypertensives. Effect of ge...

• Understanding the effects of chronic kidney disease on cardiovascular risk: a...

• Prevalence, awareness, treatment and control of hypertension in Vietnam?resul...

• Blood pressure control in the Hypertension in the Very Elderly Trial (HYVET)

• High normal blood pressure is an independent risk factor for cardiovascular d...

• Exercise blood pressure and the risk of future hypertension

• The association between aortic augmentation index and cardiovascular risk fac...

• Assessment of differences between repeated pulse wave velocity measurements i...

• The effects of dietary patterns on plasma renin activity: results from the Di...

• Systemic determinants of gene evolution and function