In Polynesia, the complex Society Islands chiefdoms constructed elaborate temples (marae), some of which reached monumental proportions and were associated...
During normal development and in disease, cohesive tissues undergo rearrangements that require integration of signals from cell adhesions to neighboring...
In complex organisms, caspase proteases mediate a variety of cell behaviors, including proliferation, differentiation, and programmed cell death/apoptosis. Structural homologs...
The most remarkable outcome of a gene duplication event is the evolution of a novel function. Little information exists on...
To compare circadian gene expression within highly discrete neuronal populations, we separately purified and characterized two adjacent but distinct groups...
Long-term experience through development and evolution and shorter-term training in adulthood have both been suggested to contribute to the optimization...
Does information irrelevant to government performance affect voting behavior? If so, how does this help us understand the mechanisms underlying...
It is commonly assumed but not proven that microRNAs (miRNAs) and their targets coevolve. Under this assumption, miRNAs and targets...
Several patterns of brain allometry previously observed in mammals have been found to hold for sharks and related taxa (chondrichthyans)...
The role of geographic isolation in marine microbial speciation is hotly debated because of the high dispersal potential and large...
The harvester ant, Pogonomyrmex occidentalis, is characterized by high levels of intracolonial genetic diversity resulting from multiple mating by the...
The hallmark of social insects is their caste system: reproduction is primarily monopolized by queens, whereas workers specialize in the...
Uncovering general principles of genome evolution that are time-invariant and that operate in germ and somatic cells has implications for...
A significantly increased risk for dominant sensorineural deafness in patients who have Hirschsprung disease (HSCR) caused by endothelin receptor type...
Estrogen receptors (ERs) protect pancreatic islet survival in mice through rapid extranuclear actions. ER also enhances insulin synthesis in cultured...
Stress affects the hippocampus, a brain region crucial for memory. In rodents, acute stress may reduce density of dendritic spines,...
The cerebral cortex of the human infant at term is complexly folded in a similar fashion to adult cortex but...
Neurofibromatosis type I (NF1) is one of the most common single-gene causes of learning disabilities. Here, we use behavioral working...
Transmissible spongiform encephalopathies are fatal neurodegenerative diseases caused by the conversion of prion protein (PrPC) into an infectious isoform (PrPSc)....
The strength of selection in populations has traditionally been inferred by measuring changes in bulk population parameters, such as mean...
A large body of research has demonstrated that variation in competitive behavior across species and individuals is linked to variation...
mTOR-generated signals play critical roles in growth of leukemic cells by controlling mRNA translation of genes that promote mitogenic responses....
Aurora kinase B inhibitors induce apoptosis secondary to polyploidization and have entered clinical trials as an emerging class of neocytotoxic...
The mammalian neocortex mediates complex cognitive behaviors, such as sensory perception, decision making, and language. The evolutionary history of the...
Genes and prior experience both influence the behavior of animals, but the relative contribution of each to fighting behavior in...
The perforant path (PP) undergoes synaptic changes in the course of aging and dementia. Previous studies attempting to assess the...