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Proceedings of the National Academy of Sciences
• The risk of a wrong conclusion: On testosterone and gender differences in ris...• Reply to Joel and Tarrasch: On the relationship between testosterone, gender,...
• Solar-powered drip irrigation enhances food security in the Sudano-Sahel [Sus...
Meeting the food needs of Africa’s growing population over the next half-century will require technologies that significantly improve rural livelihoods...
• Competition-colonization dynamics in an RNA virus [Evolution]
During replication, RNA viruses rapidly generate diverse mutant progeny which differ in their ability to kill host cells. We report...
• Molecular and functional basis of phenotypic convergence in white lizards at ...
There are many striking examples of phenotypic convergence in nature, in some cases associated with changes in the same genes....
• Homeotic effects, somitogenesis and the evolution of vertebral numbers in rec...
The development of distinct regions in the amniote vertebral column results from somite formation and Hox gene expression, with the...
• Rapid evolution of stability and productivity at the origin of a microbial mu...
Mutualistic interactions are taxonomically and functionally diverse. Despite their ubiquity, however, the basic ecological and evolutionary processes underlying their origin...
• An end-joining repair mechanism in Escherichia coli [Genetics]
Bridging broken DNA ends via nonhomologous end-joining (NHEJ) contributes to the evolution and stability of eukaryote genomes. Although some bacteria...
• Mobile elements reveal small population size in the ancient ancestors of Homo...
The genealogies of different genetic loci vary in depth. The deeper the genealogy, the greater the chance that it will...
• Impact of generalized brain arousal on sexual behavior [Neuroscience]
Although there is an extensive amount known about specific sensory and motor functions of the vertebrate brain, less is understood...
• Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission...
Long-term depression (LTD) is an important synaptic mechanism for limiting excitatory influence over circuits subserving cognitive and emotional behavior. A...
• Dog genome evolution: A strategy to segregate biogeographic effects from huma...
• Chiral porphyrazine near-IR optical imaging agent exhibiting preferential tum...
A chiral porphyrazine (pz), H2[pz(trans-A2B2)] (247), has been prepared that exhibits preferential in vivo accumulation in the cells of tumors....
• Dental maturational sequence and dental tissue proportions in the early Upper...
Neandertals differ from recent and terminal Pleistocene human populations in their patterns of dental development, endostructural (internal structure) organization, and...
• Sex, mixability, and modularity [Evolution]
The assumption that different genetic elements can make separate contributions to the same quantitative trait was originally made in order...
• African great apes are natural hosts of multiple related malaria species, inc...
Plasmodium reichenowi, a chimpanzee parasite, was until very recently the only known close relative of Plasmodium falciparum, the most...
• Latent regeneration abilities persist following recent evolutionary loss in a...
Regeneration abilities have been repeatedly lost in many animal phyla. However, because regeneration research has focused almost exclusively on highly...
• Lack of evolvability in self-sustaining autocatalytic networks constraints me...
A basic property of life is its capacity to experience Darwinian evolution. The replicator concept is at the core of...
• Leveraging skewed transcript abundance by RNA-Seq to increase the genomic dep...
Assembling the tree of life is a major goal of biology, but progress has been hindered by the difficulty and...
• Differential effects and rates of normal aging in cerebellum and hippocampus ...
Cognitive functions show many alternative outcomes and great individual variation during normal aging. We examined learning over the adult life...
• Evolution in Health and Medicine Sackler Colloquium: Evolutionary perspective...
• Evolution in Health and Medicine Sackler Colloquium: A public choice framewor...
Control measures used to limit the spread of infectious disease often generate externalities. Vaccination for transmissible diseases can reduce the...
• Evolution in Health and Medicine Sackler Colloquium: Evolution and public hea...
Evolution and its elements of natural selection, population migration, genetic drift, and founder effects have shaped the world in which...
• Evolution in Health and Medicine Sackler Colloquium: Genetic variation in hum...
Telomere length in humans is emerging as a biomarker of aging because its shortening is associated with aging-related diseases and...
• Evolution in Health and Medicine Sackler Colloquium: Evolution of the human l...
Humans have evolved much longer lifespans than the great apes, which rarely exceed 50 years. Since 1800, lifespans have doubled...
• Colloquium Papers: Transfers and transitions: Parent-offspring conflict, geno...
Human offspring are weaned earlier than the offspring of other great apes but take longer to reach nutritional independence. An...
• Evolution in Health and Medicine Sackler Colloquium: Comparative genomics of ...
We used data from studies of copy-number variants (CNVs), single-gene associations, growth-signaling pathways, and intermediate phenotypes associated with brain growth...
• Evolution in Health and Medicine Sackler Colloquium: The comparative genomics...
RNA viruses are the main agents of emerging and re-emerging diseases. It is therefore important to reveal the evolutionary processes...
• Colloquium Papers: Adaptive landscapes and protein evolution [Colloquium]
The principles governing protein evolution under strong selection are important because of the recent history of evolved resistance to insecticides,...
• Evolution in Health and Medicine Sackler Colloquium: Genetic architecture of ...
A model is investigated in which mutations that affect a complex trait (e.g., heart disease) also affect fitness because the...
• Evolution in Health and Medicine Sackler Colloquium: Stochastic epigenetic va...
Neo-Darwinian evolutionary theory is based on exquisite selection of phenotypes caused by small genetic variations, which is the basis of...
• Evolution in Health and Medicine Sackler Colloquium: Genomic disorders: A win...
Gene duplications alter the genetic constitution of organisms and can be a driving force of molecular evolution in humans and...
• Colloquium Papers: Heritability of reproductive fitness traits in a human pop...
The genetic basis of fitness traits has been studied widely in animals, yet the contribution of genetic variation to these...
• Evolution in Health and Medicine Sackler Colloquium: Consanguinity, human evo...
There is little information on inbreeding during the critical early years of human existence. However, given the small founding group...
• Colloquium Papers: Natural selection in a contemporary human population [Coll...
Our aims were to demonstrate that natural selection is operating on contemporary humans, predict future evolutionary change for specific traits...
• Evolution in Health and Medicine Sackler Colloquium: Making evolutionary biol...
New applications of evolutionary biology in medicine are being discovered at an accelerating rate, but few physicians have sufficient educational...